BIN3800 Bioinformatics

When you finish this unit, you should be able to:

1. 1

   Describe recent advances in genomics;

2. 2

   Navigate genomic and proteomic databases in a variety of species;

3. 3

   Use Linux, Python and R to query big data (DNA, RNA or amino acid sequences);

4. 4

   Identify conserved features in nucleotide sequences and define functional domains;

5. 5

   Identify sequences and data on mutations associated with human diseases;

6. 6

   Interpret structural and functional effects of mutations and predict molecular mechanisms underlying the resulting disease;

7. 7

   Construct and analyse sequence alignments, molecular phylogeny and molecular models using nucleotide or amino acid sequences.