Physical chemistry 2: Solutions, surfaces and solids

Solutions, self-assembled systems, multiphase liquid systems and the properties of solids that yield pharmaceutical solutions are key to the performance and manufacture of pharmaceutical products. This unit aims to build on Physical Chemistry I (BPS1031) to provide you with a firm understanding of the physical chemistry that underpins the properties and dissolution of pharmaceutical solids and additives to form solutions. In particular, an understanding of the physicochemical properties of pharmaceutical solids (drugs and excipients), their transfer into solution form and the properties of those solutions from a pharmaceutical science perspective will set the foundation for you to understand the impact of these properties and concepts in pharmaceutical and other formulated products. The key concepts are related directly to aspects of a suite of representative pharmaceutical products allowing you to put the concepts into a relevant context. The understanding of these principles will also assist you in your understanding in some areas of chemistry, physiology and biology.

This will involve:

• physical chemistry of solutions
• solids, semisolids and solubility
• interfacially active molecules and their use in formulation