UnitLevel 3Undergraduate

BTH3260 Microbiome science

Faculty of Science

BTH3260 Microbiome science is a level 3, 6-credit-point, undergraduate unit from the Faculty of Science, offered in 2027 in Semester 2 at Malaysia. It needs BTH2830.

Credit points
6
Offered in 2027
Semester 2
Malaysia
Assessment
No exam
4 tasks

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Requisites

Before BTH3260

Prerequisites

Pass these before you enrol.

After BTH3260

No unit lists BTH3260 as a prerequisite in the 2027 handbook.

Overview

This unit offers a comprehensive introduction to the rapidly evolving field of studying microbial communities and their collective genomes across diverse environments. This third-year unit explores the fundamental ecological principles governing microbiomes and their crucial roles in human, animal, and environmental health. You will investigate the link between the microbiome and various health and disease states, particularly focusing on host-microbe interactions. A key focus is integrating theoretical knowledge with practical skills. The unit combines essential wet-laboratory techniques for sample processing and sequencing preparation with an intensive block of bioinformatics training, covering command-line tools, 16S rRNA data analysis, statistical interpretation, data visualisation, functional prediction, and an introduction to metagenomics. Emphasis is placed on developing critical evaluation skills through literature analysis and effective communication of complex scientific concepts. This unit will equip you with foundational knowledge and the integrated skillset required for further study or careers in biotechnology, biomedical research, and related fields requiring microbiome expertise.

Offerings in 2027

Teaching periodCampusMode
Second semesterMalaysiaOn campus

Assessment

  • Research proposalWritten
    25%
  • Mid-term assessmentExercise
    30%
  • Data analysis and reportWritten
    30%
  • Mini symposiumPresentation
    15%

Assessment details may change. Please refer to the assessment information in Moodle closer to the start of the teaching period.

Learning outcomes

When you finish this unit, you should be able to:

  1. 1

    Explain by defining fundamental terms like microbiota, diversity and dysbiosis, and describe the ecological principles such as resource utilization, interspecies interactions, and community dynamics like succession and stability that shape microbial communities.;

  2. 2

    Describe the established and emerging functions of the microbiome in various contexts, including human health, animal health, and environmental processes;

  3. 3

    Describe the established and emerging functions of the microbiome in various contexts, including human health, animal health, and environmental processes;

  4. 4

    Demonstrate the ability to use basic bioinformatic tools and analytical methods to process, analyse, and interpret microbiome datasets, including assessing microbial diversity and taxonomic composition;

  5. 5

    Critically evaluate and synthesise information from primary scientific literature and other sources regarding microbiome research and applications, and effectively communicate complex scientific concepts related to the field of microbiome science.

Workload and teaching

  • Workshops24 hours
  • Laboratories30 hours
  • Teaching approachProblem-based learning
  • Teaching approachActive learning
  • Teaching approachRole play
  • Teaching approachCase-based teaching
  • One 1-hour pre-recorded lectures;
  • One 2-hour workshop;
  • One 3-hour  lab class for 10 weeks and
  • Six to seven hours of independent study per week.

You will encounter this approach when you collaboratively define a research problem and design a study for your research proposal. The bioinformatics labs inherently involve problem-solving as students troubleshoot analyses, and the individual data analysis report requires you to apply your skills to solve the specific analytical problem presented by the dataset.

Active Learning will be used throughout this unit to ensure you directly engage with the material. This occurs through hands-on participation in scheduled workshops, wet labs and bioinformatics lab sessions focused on data analysis techniques. You will also actively learn during data exploration activities, collaborative work on group projects like the  mini-symposium, participation in class discussions, and by completing the individual data analysis report.

Role-Play will be used to develop communication skills. You will engage in role-play during the mini-symposium assessment, where presenters adopt the role of experts and the audience acts as questioning peers. Further opportunities for role-play will be incorporated into class activities, such as simulating explanations of complex data to different audiences.

This approach will be used to explore complex topics and develop analytical skills by examining specific scenarios. It features mainly in sections dedicated to the human microbiome in health and disease, where case studies will illustrate key concepts. It will also be applied when discussing real-world examples during lectures.

Learning resources

Recommended resources

  • Microbiomes health and the environment

Dylan Parks

  • An Introduction to the Microbiome in Health and Diseases

Adetunji, Charles Oluwaseun ; Michael, Olugbenga Samuel ; Esiobu, N ; Aluko, Rotimi E

  • Bioinformatic and Statistical Analysis of Microbiome Data: From Raw Sequences to Advanced Modeling with QIIME 2 and R

Xia, Yinglin ; Sun, J

Contacts

Chief Examiners
Dr Tan Hock Siew
Unit Coordinators
Dr Tan Hock Siew

Common questions

What are the prerequisites for BTH3260?

You need BTH2830 before you enrol.

When is BTH3260 offered?

In 2027, BTH3260 runs in Semester 2 at Malaysia.

Does BTH3260 have an exam?

No. BTH3260 has 4 assessment tasks and no exam.

More details

Credit points
6
Level
3
Study level
Undergraduate
Faculty
Faculty of Science
Type
Coursework
EFTSL
0.125
Student contribution
SCA Band 2
Study abroad
Available
Handbook years
20262027