GNA5042 Cancer genomics
Faculty of Science
GNA5042 Cancer genomics is a level 5, 12-credit-point, postgraduate unit from the Faculty of Science, offered in 2026 in Semester 1 at Clayton. It has no prerequisites.
- Credit points
- 12
- Offered in 2026
- Semester 1
- Clayton
- Assessment
- No exam
- 5 tasks
- Workload
- 24 hours
- per semester
This is the 2026 handbook entry. See the 2027 entry.
Reviews
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Requisites
Before GNA5042
No prerequisites or corequisites besides the enrolment rules below.
After GNA5042
No unit lists GNA5042 as a prerequisite in the 2026 handbook.
Enrolment rules
COREQUISITE: Must be enrolled in Master of Genome Analytics or Graduate Diploma of Genome Analytics (or with permission from the unit coordinator).
PREREQUISITE: GNA5120
Overview
This unit will enable you to gain knowledge on the application of genome sequencing in the diagnoses and clinical management of cancer. You will learn about the different mechanisms that drive cancers and how integrative -omics can be applied to understanding cancer. You will learn about the types of somatic and germline cancer mutations that develop and how they are identified. You will apply genome curation techniques to analyse cancer genomes and learn how to identify clinically relevant sequence variants. The unit is designed to develop real-world skills in using cancer genome databases and generating clinical genome analysis reports.
Offerings in 2026
| Teaching period | Campus | Mode |
|---|---|---|
| First semester | Clayton | On campus |
Assessment
- Video reportPresentation15%
- Oral presentationPresentation10%
- QuizzesQuiz / Test10%
- Test design and validation of a genomics test reportDemonstration30%
- Case reportWritten35%
Assessment details may change. Please refer to the assessment information in Moodle closer to the start of the teaching period.
Learning outcomes
When you finish this unit, you should be able to:
- 1
Evaluate the different mechanisms that drive cancer and explain why genomic heterogeneity is common in cancer cells;
- 2
Evaluate how integrative ‘omics’ can be applied to understanding cancer and evaluate the use of databases in cancer genome analysis and diagnosis;
- 3
Assess how precision medicine can be used in cancer treatment;
- 4
Apply genome curation approaches to analyse cancer genomic sequences;
- 5
Apply skills to critically select different ‘omic’ tools to help answer research questions in cancer;
- 6
Evaluate how cancer genomics impacts diagnosis, treatment selection, and outcome prediction;
- 7
Examine the clinical utility of current and emerging genomics applications in the clinical cancer laboratory setting;
- 8
Evaluate the disease mechanisms and clinical features of specific cancer types, and define and justify their associated genomic testing strategies;
- 9
Critically review the scientific literature relating to cancer;
- 10
Communicate research outcomes in verbal and written form using appropriate tools to a scientific audience.
Workload and teaching
- Workshops72 hours
- Teaching approachOnline learning
- Teaching approachActive learning
- Teaching approachCase-based teaching
- Teaching approachProblem-based learning
A total of 24 hours per week including 12 hours of directed learning such as lectures (online), workshops, and online activities and 12 hours of self-directed study.
Educational content, exercises and interactive lessons will be provided in the online-learning environment. All lecture material will be provided online so as to ensure face to face time is spent in workshops and active-based learning.
A total of 24 hours per week including 12 hours of directed learning such as lectures (online), workshops, and online activities and 12 hours of self-directed study.
You will be presented with patient cases that require genome analytics techniques to be applied. These techniques will first be taught in interactive workshops and then you will apply these techniques to the cases they are provided.
The online and activity learning will both involve problem-based learning, where you must apply your knowledge to new problems.
Learning resources
Recommended resources
References to relevant training materials in the scientific literature and Moodle lessons to introduce concepts and develop skills.
Contacts
- Unit Coordinators
- Professor Colby Zaph
- Associate Professor Joseph Rosenbluh
- Chief Examiners
- Associate Professor Peter Boag
Common questions
What are the prerequisites for GNA5042?
GNA5042 has no prerequisites, but enrolment rules apply.
When is GNA5042 offered?
In 2026, GNA5042 runs in Semester 1 at Clayton.
How much work is GNA5042?
The handbook expects about 24 hours of study across the semester. No students have rated its difficulty yet.
Does GNA5042 have an exam?
No. GNA5042 has 5 assessment tasks and no exam.