MCE5212 Genetic testing in ART

This unit will provide a detailed understanding of the molecular biology and genetic diagnostic techniques utilised in Assisted Reproductive Technology (ART) programs. Students will be taught the differences between Pre Implantation Screening (PGS) by array techniques, pre-implantation genetic diagnosis (PGD) of singe gene disorders and non-invasive pre-natal testing. This knowledge is enhanced by learning how biopsies are performed on embryos, how the biopsied cells are processed for the various different genetic tests, and how these tests are interpreted in a clinical setting On completion, students will possess a sound theoretical knowledge and understanding of the molecular and genetic techniques used in a clinical human genetics laboratory, and also be familiar with the different practical applications of these techniques. They will also appreciate ethical implications and societal expectation in PGS and PGD.