Metabolic basis of human diseases

This is the second of two units in the Biochemistry second year curriculum which introduces you to the fundamental concepts and knowledge required to understand cellular function at a molecular level. The unit will assist you to build the skills necessary to interpret biochemical information and perform biochemical experiments. The curriculum builds on foundational knowledge of cell biology and organic and physical chemistry, establishes the skills and understanding needed for the more specialised third year biochemistry units. It also provides you with a broad appreciation of cellular processes relevant to all areas of life.

In this unit (Metabolic basis of human diseases), you will learn about the mechanisms by which biochemical processes are activated, suppressed and coordinated in pathways/networks to maintain cell and organism viability and to respond appropriately to environmental stimuli. These mechanisms are examined within the context of cellular respiration and energy metabolism and the dysregulation of biochemical pathways is related to human disease. Skill development focuses on analysis and measurement of metabolic and signalling processes and on testing hypotheses related to biochemical pathways and networks.