BPS3232 Molecular basis of drug action

When you finish this unit, you should be able to:

1. 1

   Explain central concepts relating to the interaction of endogenous ligands, drugs and therapeutic targets, including:

   • Common receptor classes, agonism/antagonism, inverse agonism and allosteric modulation
   • Enzyme classes including metalloenzymes, their reactions and kinetic properties, and enzyme inhibition
   • DNA oligonucleotide recognition and modification by ligands
   • Peptidomimetics
   • Small molecule structure-activity relationships
2. 2

   Apply common design approaches (ligand-based, structure-based and mechanism-based design strategies) to propose drug molecules for therapeutic targets

3. 3

   Acquire skills in researching information and to present the findings in a structured, logical and fluent manner;

   
   
   

4. 4

   Effectively work in a team to plan, conduct and complete an inquiry project.