BPS2021 Synthetic chemistry 1: Structure and reactivity
Faculty of Pharmacy and Pharmaceutical Sciences
BPS2021 Synthetic chemistry 1: Structure and reactivity is a level 2, 6-credit-point, undergraduate unit from the Faculty of Pharmacy and Pharmaceutical Sciences, offered in 2027 in Semester 1 at Malaysia and Parkville. It needs BPS1011, BPS1012, BPS1021, BPS1022, BPS1031, BPS1032, BPS1041 and BPS1042 and unlocks 13 units.
- Credit points
- 6
- Offered in 2027
- Semester 1
- Malaysia, Parkville
- Assessment
- Exam 52%
- and 3 other tasks
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Requisites
Before BPS2021
Prerequisites
Pass these before you enrol.
- BPS1011Human physiology 1: Cells to systemsNo reviews yet
- BPS1012Human physiology 2: Body systemsNo reviews yet
- BPS1021Medicinal chemistry 1: StructureNo reviews yet
- BPS1022Medicinal chemistry 2: Reactivity and biomoleculesNo reviews yet
- BPS1031Physical chemistry 1: Equilibria and changeNo reviews yet
- BPS1032Physical chemistry 2: Solutions, surfaces and solidsNo reviews yet
- BPS1041Scientific inquiryNo reviews yet
- BPS1042Pharmaceutical science in contextNo reviews yet
After BPS2021
13 units list BPS2021 as a prerequisite or corequisite.
- BPS3011Disease-focused pharmacologyNo reviews yet
- BPS3012Applied pharmaceutical science: From concept to marketNo reviews yet
- BPS3021BiotechnologyNo reviews yet
- BPS3022Microbiology and immunologyNo reviews yet
- BPS3031Computational drug designNo reviews yet
- BPS3032Toxicology and advanced pharmacology No reviews yet
- BPS3041Synthetic chemistry 2: Advanced methodsNo reviews yet
- BPS3042Advanced experimental spectroscopyNo reviews yet
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Overview
The ability to make or modify small molecules and confirm the identity of synthetic products is fundamental to the drug discovery and development process. Synthetic Chemistry I: Structure and Reactivity introduces you to the theoretical principles and practical tools of chemical synthesis by examining the reactivity of several common functional groups both inside and outside of the lab. This approach is relevant not only to direct synthetic applications, but also to drug design, drug-target interactions, and drug formulation more generally.
You will examine mechanisms involving alkenes and alkynes, benzene derivatives, alcohols, alkyl halides, and carbonyls, along with justifications for their occurrence. These core skills will enable you to propose single- and multi-step synthetic mechanisms to produce target molecules. Key analytical techniques used to elucidate organic compounds will also be explored, which will enable you to analyse and determine the structural identity of synthetic products.
Offerings in 2027
| Teaching period | Campus | Mode |
|---|---|---|
| First semester | Malaysia | On campus |
| First semester (extended) | Parkville | On campus |
Assessment
- Workshop quizzesQuiz / Test15%
- Mid-semester testsWritten15%
- Laboratory-based activitiesProject18%
- Laboratory-based examProject12%
- End of semester asessmentExamination40%
Assessment details may change. Please refer to the assessment information in Moodle closer to the start of the teaching period.
Learning outcomes
When you finish this unit, you should be able to:
- 1
Analyse the chemical structure of pharmaceutical compounds using a functional group approach to determine their properties and reactivity
- 2
Formulate both single-step and multi-step reaction mechanisms using arrow-pushing formalisms, and rationalise these mechanisms using kinetic and thermodynamic principles
- 3
Describe the physical basis of selected spectroscopic techniques and explain their role in the identification of drug molecules
- 4
Systematically analyse and interpret spectroscopic data using common analytical techniques to identity small molecule products, and characterise distinct molecular properties
- 5
Demonstrate safe and effective chemical synthesis, product purification and characterisation techniques within a working laboratory environment, both individually and in team-based roles
- 6
Analyse, discuss, and evaluate experimental data via written scientific reports, using appropriate scientific language and ethical GenAI usage as expected of academic standards
Workload and teaching
- Assessments4 hours
- Workshops12 hours
- Laboratories24 hours
- Applied sessions2 hours
- Teaching approachProblem-based learning
- Teaching approachOnline learning
- Teaching approachEnquiry-based learning
- Teaching approachActive learning
Twelve 1-hour online preparation modules (discovery)
Twenty-four 1-hour lectures (online modules)
One 2 hour Introductory Applied session
Six 2-hour workshops
Six 4-hour laboratories
Up to four hours of scheduled in-semester assessments
Problem solving workshops
Moodle discovery modules, 'check your learning' questions, and interactive lectures
Laboratory experiments
Interactive lectures and workshops
Learning resources
Required resources
“Organic Chemistry” by Buice. Specifically:
Bruice, P. Y. (2016). Organic chemistry (Eighth edition. Global edition.). Pearson Education.
This resource can be accessed by students electronically through the Monash Library.
Contacts
- Unit Coordinators
- Dr Ng Jia Hui
- Dr Manuela Jorg
- Chief Examiners
- Dr Manuela Jorg
Common questions
What are the prerequisites for BPS2021?
You need BPS1011, BPS1012, BPS1021, BPS1022, BPS1031, BPS1032, BPS1041 and BPS1042 before you enrol.
What can I take after BPS2021?
BPS2021 is a prerequisite or corequisite for 13 units, including BPS3011, BPS3012, BPS3021, BPS3022, BPS3031 and BPS3032.
When is BPS2021 offered?
In 2027, BPS2021 runs in Semester 1 at Malaysia and Parkville.
Does BPS2021 have an exam?
Yes. The exam is worth 52% of the final mark, alongside 4 other tasks.