UnitLevel 2Undergraduate

BPS2021 Synthetic chemistry 1: Structure and reactivity

Faculty of Pharmacy and Pharmaceutical Sciences

BPS2021 Synthetic chemistry 1: Structure and reactivity is a level 2, 6-credit-point, undergraduate unit from the Faculty of Pharmacy and Pharmaceutical Sciences, offered in 2027 in Semester 1 at Malaysia and Parkville. It needs BPS1011, BPS1012, BPS1021, BPS1022, BPS1031, BPS1032, BPS1041 and BPS1042 and unlocks 13 units.

Credit points
6
Offered in 2027
Semester 1
Malaysia, Parkville
Assessment
Exam 52%
and 3 other tasks

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Requisites

Overview

The ability to make or modify small molecules and confirm the identity of synthetic products is fundamental to the drug discovery and development process. Synthetic Chemistry I: Structure and Reactivity introduces you to the theoretical principles and practical tools of chemical synthesis by examining the reactivity of several common functional groups both inside and outside of the lab. This approach is relevant not only to direct synthetic applications, but also to drug design, drug-target interactions, and drug formulation more generally.

You will examine mechanisms involving alkenes and alkynes, benzene derivatives, alcohols, alkyl halides, and carbonyls, along with justifications for their occurrence. These core skills will enable you to propose single- and multi-step synthetic mechanisms to produce target molecules. Key analytical techniques used to elucidate organic compounds will also be explored, which will enable you to analyse and determine the structural identity of synthetic products.

Offerings in 2027

Teaching periodCampusMode
First semesterMalaysiaOn campus
First semester (extended)ParkvilleOn campus

Assessment

  • Workshop quizzesQuiz / Test
    15%
  • Mid-semester testsWritten
    15%
  • Laboratory-based activitiesProject
    18%
  • Laboratory-based examProject
    12%
  • End of semester asessmentExamination
    40%

Assessment details may change. Please refer to the assessment information in Moodle closer to the start of the teaching period.

Learning outcomes

When you finish this unit, you should be able to:

  1. 1

    Analyse the chemical structure of pharmaceutical compounds using a functional group approach to determine their properties and reactivity

  2. 2

    Formulate both single-step and multi-step reaction mechanisms using arrow-pushing formalisms, and rationalise these mechanisms using kinetic and thermodynamic principles

  3. 3

    Describe the physical basis of selected spectroscopic techniques and explain their role in the identification of drug molecules

  4. 4

    Systematically analyse and interpret spectroscopic data using common analytical techniques to identity small molecule products, and characterise distinct molecular properties

  5. 5

    Demonstrate safe and effective chemical synthesis, product purification and characterisation techniques within a working laboratory environment, both individually and in team-based roles

  6. 6

    Analyse, discuss, and evaluate experimental data via written scientific reports, using appropriate scientific language and ethical GenAI usage as expected of academic standards

Workload and teaching

  • Assessments4 hours
  • Workshops12 hours
  • Laboratories24 hours
  • Applied sessions2 hours
  • Teaching approachProblem-based learning
  • Teaching approachOnline learning
  • Teaching approachEnquiry-based learning
  • Teaching approachActive learning
  • Twelve 1-hour online preparation modules (discovery)

  • Twenty-four 1-hour lectures (online modules)

  • One 2 hour Introductory Applied session

  • Six 2-hour workshops

  • Six 4-hour laboratories

  • Up to four hours of scheduled in-semester assessments

Problem solving workshops

Moodle discovery modules, 'check your learning' questions, and interactive lectures

Laboratory experiments

Interactive lectures and workshops

Learning resources

Required resources

“Organic Chemistry” by Buice. Specifically:
Bruice, P. Y. (2016). Organic chemistry (Eighth edition. Global edition.). Pearson Education.
This resource can be accessed by students electronically through the Monash Library.

Contacts

Unit Coordinators
Dr Ng Jia Hui
Dr Manuela Jorg
Chief Examiners
Dr Manuela Jorg

Common questions

What are the prerequisites for BPS2021?

You need BPS1011, BPS1012, BPS1021, BPS1022, BPS1031, BPS1032, BPS1041 and BPS1042 before you enrol.

What can I take after BPS2021?

BPS2021 is a prerequisite or corequisite for 13 units, including BPS3011, BPS3012, BPS3021, BPS3022, BPS3031 and BPS3032.

When is BPS2021 offered?

In 2027, BPS2021 runs in Semester 1 at Malaysia and Parkville.

Does BPS2021 have an exam?

Yes. The exam is worth 52% of the final mark, alongside 4 other tasks.

More details

Credit points
6
Level
2
Study level
Undergraduate
Faculty
Faculty of Pharmacy and Pharmaceutical Sciences
Type
Coursework
EFTSL
0.125
Student contribution
SCA Band 2
Study abroad
Available