BPS3041 Synthetic chemistry 2: Advanced methods

The principal aim of this unit is to provide you with a detailed knowledge of numerous aspects of synthetic organic chemistry, as it applies to modern medicinal chemistry.

The subject follows from BPS2021, covering advanced organic synthesis and methodology. Topics include catalysis in synthesis, radical chemistry, organometallic chemistry, heterocyclic chemistry, reactive intermediates and stereochemistry, as well as retrosynthetic analysis. An understanding of reaction mechanisms will be emphasised throughout. The laboratory component reinforces aspects of the lecture course with laboratory experience.

This will involve:

• catalysis and biocatalysis

• organometallic reactions

• radical reactions

• heterocyclic chemistry

• stereoselective synthesis

• pericyclic reactions

• reactive intermediates