MPS5102 Target identification and validation

When you finish this unit, you should be able to:

1. 1

   Describe the processes by which disease states can alter homeostatic and physiological functions (pathophysiology), explaining the relationship between disrupted function/s and observed signs and symptoms

2. 2

   Explain in detail how drug treatments target the pathophysiology disease states, identifying the drug target and cellular target relevant to the disease state

3. 3

   Articulate the process of target identification and validation using selected disease states as case studies, and explain how emerging technologies are integrated into the process of target identification and validation and their advantages.

4. 4

   Define the characteristics of an ideal drug target and use a systematic approach to evaluate whether exemplar therapeutics reflect these properties, proposing a rationale for why deviating from accepted drug target might be acceptable and/or necessary in certain situations

5. 5

   Use effective teamwork and collaborative skills, and research skills to develop a set of target identification and validation dossiers

6. 6

   Demonstrate oral and written communication skills appropriate for master’s students.