PHR1022 How medicines work 2: Pharmacokinetics
Faculty of Pharmacy and Pharmaceutical Sciences
PHR1022 How medicines work 2: Pharmacokinetics is a level 1, 6-credit-point, undergraduate unit from the Faculty of Pharmacy and Pharmaceutical Sciences, offered in 2027 in Semester 2 at Malaysia and Parkville. It has no prerequisites and unlocks 18 units, leading on to 19 units in all.
- Credit points
- 6
- Offered in 2027
- Semester 2
- Malaysia, Parkville
- Assessment
- Exam 40%
- and 5 other tasks
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Requisites
Before PHR1022
No prerequisites or corequisites.
After PHR1022
18 units list PHR1022 as a prerequisite or corequisite.
- PHR2011Professional practice 3No reviews yet
- PHR2012Professional practice 4No reviews yet
- PHR2021How medicines work 5: Drug deliveryNo reviews yet
- PHR2041Comprehensive care: Respiratory and gastrointestinalNo reviews yet
- PHR2042Comprehensive care: Endocrinology and renalNo reviews yet
- PHR2141Comprehensive care: Dermatology and painNo reviews yet
- PHR2142Comprehensive care: CardiovascularNo reviews yet
- PHR3041Comprehensive care: Blood, brain and cancersNo reviews yet
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- PHR3062Student experiential placements 1No reviews yet
- PHR3141Comprehensive care: Pathogens, host defence and treatmentNo reviews yet
- PHR4012Professional practice 5No reviews yet
- PHR4042Integrated careNo reviews yet
- PHR4061Student experiential placements 2No reviews yet
- PHR4142Acute care: Inquiry casesNo reviews yet
- PHR5052Inquiry and innovation methodsNo reviews yet
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Overview
This unit builds upon PHR1021 (How Medicines Work 1) to provide an overview of the processes that affect drug concentrations at target tissues in the body, including drug absorption, distribution, metabolism and excretion. These processes are all dependent on the chemical properties of the drug (which are studied in detail in PHR1222; How Medicines Work 4) and impact how much drug is available to interact with pharmacological targets (which is studied in detail in PHR1122; How Medicines Work 3). To address these key areas, you will explore the fundamentals of pharmacokinetics including the concepts of drug clearance and volume of distribution, and how these impact on secondary pharmacokinetic parameters. Together these factors ultimately impact the design and application of safe and effective therapeutic dosage regimens for patients.
Offerings in 2027
| Teaching period | Campus | Mode |
|---|---|---|
| Second semester | Malaysia | On campus |
| Second semester | Parkville | On campus |
Assessment
- Readiness Assurance testsQuiz / Test5%
- Progress testsQuiz / TestCompetency hurdle25%
- Metabolism in Action (team; poster)Written10%
- Identifying and responding to pharmacokinetic drug interactions (team; oral)Presentation10%
- Written response to doctor inquiry (individual; written)Written10%
- Final assessmentExamination40%
Assessment details may change. Please refer to the assessment information in Moodle closer to the start of the teaching period.
Learning outcomes
When you finish this unit, you should be able to:
- 1
Calculate and describe how drug clearance and volume of distribution determine the plasma concentration profile of a drug
- 2
Calculate and apply a range of secondary pharmacokinetic parameters that determine dosage regimens
- 3
Describe, define and calculate drug bioavailability
- 4
Describe and evaluate how the relationship between pharmacokinetics and pharmacodynamics determines the time-course of drug response
- 5
Calculate cumulative drug response given the pharmacokinetics and pharmacodynamics of a drug
- 6
Understand how pharmacogenomics impacts drug pharmacokinetics and response
- 7
Describe different types of pharmacokinetic drug-drug interactions and predict their impact on plasma drug concentration vs time profiles and therapeutic response
- 8
Work in teams and individually to effectively communicate (orally and written) aspects of pharmacokinetics to peers, lay people and other healthcare professionals
- 9
Work in teams and individually using a structured approach for problem solving
Workload and teaching
- Assessments3 hours
- Applied sessions24 hours
- Workshops24 hours
- Teaching approachOnline learning
- Teaching approachSimulation or virtual practice
- Teaching approachActive learning
- Teaching approachProblem-based learning
- Teaching approachCase-based teaching
- Teaching approachEnquiry-based learning
- Teaching approachRole play
- Twenty four hours of independent study
- Twenty four hours of discovery or pre-learning activities (up to 2 hours per week)
- Twenty four hours of applied classes (2 hours a week)
- Twenty four hours of small group classes including assessment (2 hours per week)
Learning resources
Technology resources
For more information on Bring Your Own Device (BYOD) specifications and the technology systems and services available to you, review the Student Technology Essentials Handbook https://www.monash.edu/__data/assets/pdf_file/0010/1041220/student-it-brochure.pdf
Contacts
- Chief Examiners
- Professor Natalie Trevaskis
- Unit Coordinators
- Professor Natalie Trevaskis
- Dr How Chee Wun
Common questions
What are the prerequisites for PHR1022?
PHR1022 has no prerequisites.
What can I take after PHR1022?
PHR1022 is a prerequisite or corequisite for 18 units, including PHR2011, PHR2012, PHR2021, PHR2041, PHR2042 and PHR2141. Those lead on to 19 units in all.
When is PHR1022 offered?
In 2027, PHR1022 runs in Semester 2 at Malaysia and Parkville.
Does PHR1022 have an exam?
Yes. The exam is worth 40% of the final mark, alongside 5 other tasks.